熊永爱，男，博士，博士后，必赢线路检测3003no1副教授，硕士研究生导师。
2016年毕业于成都中医药大学，获中药学博士学位。2017年赴美国UNMC从事博士后研究工作（方向为新型药物递送系统设计）；2019年至2021年在深圳大学必赢线路检测3003no1从事博士后研究工作（方向为天然产物抗病毒/抗肿瘤作用研究）。目前主要从事天然活性产物调控细胞程序性死亡抗病毒、抗肿瘤和纳米递药系统研究。主持和参与国家自然科学基金2项，省部级科研项目3项，横向科研项目10项。在Trends Food Sci Tech、J Mol Cell Biol、Int J Nano、J Med Virol、Int J Pharmaceut等国际刊物上发表SCI论文50余篇。H-index为20，Citations为400次。担任Theranostics、Viruses、Fronters in Pharmacology、Drug Delivery等杂志审稿人。学术任职：中华中医药学会中成药分委会理事、中国药理学会表观遗传药理学委员。社会任职：担任贵州新科金钗石斛研究院副院长、贵州省科技特派员。
长期从事贵州地区中药民族药药效物质挖掘和大健康产品开发，擅长院内制剂开发、保健品、食品、妆字号产品等设计研发和注册申报。秉承科学研究服务产业的理念，为省内企业产品开发和技术攻关做出了突出贡献，2022年被评为优秀科技特派员。
1.天然产物调控细胞程序性死亡抗病毒、抗肿瘤作用和机制研究
2.基于炎症/癌症微环境响应的药物递送系统研究
1.国家自然科学基金，基于GCN5乙酰化修饰调控TFEB-自噬溶酶体通路探讨辣木籽活性成分MoringaA广谱抗流感病毒的作用及机制，2023-2026，34万，主持
2.贵州省科技厅支撑计划，基于TNF-β通路的辣木籽活性成分MoringaA抗甲型H1N1的作用机制研究与示范，2021-2024，32万，主持
3.贵州省科技厅基础研究计划，骨髓抑制激发的造血干细胞自噬对白细胞影响的分子机制及地榆皂苷的调控作用研究，2018-2021，30万，主持
4.国家自然科学基金，基于Sirt3/Nrf2抗氧化途径研究淫羊藿次苷Ⅱ预处理对脑缺血-再灌注损伤的保护作用，2018-2021，34万元，参与
1.Yongai Xiong.The emerging role of PANoptosis in cancer treatment[J].Biomedicine&Pharmacotherapy.2023. (IF=7.5)
2.Yukai Huang, Xuerui Zhu, Xiao Guo, Yuancheng Zhou, Dongying Liu, Jingrui Mao, Yongai Xiong, Youcai Deng, Xinghong Gao. Advances in mRNA vaccines for viral diseases[J]. Journal of Medical Virology.2023.(IF=12.7)
3.HongWang, Lei Chen,Yongai Xiong*, et al.Polydopamine-coated mesoporous silica nanoparticles co-loaded with Ziyuglycoside I and Oseltamivir for synergistic treatment of viral pneumonia[J]. International Journal of Pharmaceutics.2023.(IF=5.8)
4.Yongai Xiong*,Tingting Chen, Lei Chen,et al.Gold Nanoparticles Coated with SH-PEG-NH2 and Loaded with Ziyuglycoside I for Promoting Autophagy in Hematopoietic Stem Cells[J].International Journal of Nanomedicine, 2023.(IF=8.0）
5.Lei Chen, Tingting Chen, Yongai Xiong*, etal.Recent advances in the study of the immune escape mechanism of SFTSV and its therapeutic agents[J].Viruses, 2023.(IF=5.8)
6.Xiao Guo, Xinghong Gao,Yongai Xiong*, etal.Clinical advances in non-replication structure mRNA vaccines of viral diseases[J].Virology Journal, 2023.(IF=5.9)
7.Liangyu Yang, Lei Chen,Yongai Xiong*,et al.The crosstalk between classic cell signaling pathways, non-coding RNAs and ferroptosis in drug resistance of tumors[J].Cellular Signalling, 2023. (IF=4.8)
8.Yue Liu,Liangyu Yang,Yongai Xiong*,et al. RecentAdvances in Antiviral Activities of Triterpenoids[J]. Pharmaceuticals, 2022.(IF=4.8)
9.Lixia Wang, Yongai Xiong*, Yuzhu Tan*,et al. Review of lignans from 2019 to 2021: Newly reported compounds, diverse activities, structure-activity relationships and clinical applications[J]. Phytochemistry, 2022.(IF=4.0)
10.Yongai Xiong.,Riaz Rajoka MS,He Zhendan, etal. Isolation and identification of two new compounds from the seeds of Moringa oleifera and their antiviral and anti-inflammatory activities[J]. Nat Prod Res. 2022.(IF=2.2)
11.Yongai Xiong.,Yandong Tang., Chunfu Zheng. Thecrosstalk betweencaspases family and cGAS-STING signaling pathway[J]. Journal of Molecular Cell Biology (JMCB), 2021.(IF=8.2)
12.Mahmoud Youssef, Hanaa Y. Ahmed, Yongai Xiong *,et al. Probiotic supplements: their strategies in the therapeutic and prophylactic of threatening human life diseases[J]. International Journal of Molecular Sciences, 2021.(IF=6.2)
13.Tingting Song#., Hong Wang#.,Yongai Xiong*., et al.TPGS-modified Long-circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression[J]. International Journal of Nanomedicine, 2021.(IF=8.0）
14.Mehwish H.M., Shahid Riaz R.Muh,Yongai Xiong, et al. Therapeutic potential of Moringa seed polysaccharide embedded silver nanoparticles in wound healing [J].International Journal of Biological Macromolecules, 2021.(IF=8.0）
15.Yongai Xiong, Shahid Riaz M, Zhendan H, et al.Virucidal activity ofMoringaA fromMoringa oleiferaseeds against Influenza A Viruses by regulating TFEB[J].Int Immunopharmacology, 2021.(IF=5.7)
16.Shahid Riaz R.Muh,Mehwish H.M.,Yongai Xiong,et al.Gut microbiota targeted , nanomedicine for cancer therapy: Challenges and future considerations[J].Trends in Food Science & Technology, 2020. (IF=16.0)
17.Shahid Riaz R.Muh,Mehwish H.M.,Yongai Xiong,et al. Green synthesis of a silver nanoparticle using Moringa oleifera seed and its applications for antimicrobial and sun-light mediated photocatalytic water detoxification[J].Journal of Environmental Chemical Engineering, 2021.(IF=7.0)
18.Zhang M, Chen T,Yongai X,et al. Peroxide- and transition metal-free electrochemical synthesis of α,β-epoxy ketones[J].Organic&Biomolecular Chemistry,2021.(IF=4.1)
19.Ji Chen, Yanqiao Ma,Yongai Xiong,et al.Formulation and evaluation of a topical liposomal gel containing a combination of zedoary turmeric oil and tretinoin for psoriasis activity[J].Journal of Liposome Research,2020.(IF=5.6)
20.Yongai Xiong,Ya Z, Wang S, et al. Development and In Vivo Evaluation of Ziyuglycoside I-Loaded Self-Microemulsifying Formulation for Activity of Increasing Leukocyte[J].AAPS PharmSciTech, 2019.(IF=4.0)
21.Chen L; Liu CS;Xiong Yongai,et al. Characterization, pharmacokinetics and tissue distribution of chlorogenic acid-loaded self-microemulsifying drug delivery system[J].European Journal of Pharmaceutical Sciences, 2017.(IF=5.1)
22.王宏，刘月，熊永爱*，等.生物碱类化合物抗病毒活性及其机制研究进展[J].中草药，2022，53(09):2839-2850.
23.王宏，刘月，熊永爱*，等.辣木籽油对慢性高脂血症小鼠的降脂作用[J].中国油脂，2022，47（7）:66-70.
24.宋婷婷，蔡荣珊，熊永爱*，等.TPGS 修饰的地榆皂苷 I 长循环脂质体的制备及质量评价[J].中草药，2021，52(12):3522-3529.
25.蔡荣珊，王宏，熊永爱*，等.基于RNA-seq技术研究地榆皂苷I保护小鼠造血干细胞的转录组学特征[J].中药药理与临床，2021，37(4):13-17.
26.熊永爱*，邹娅，王森，等.地榆皂苷Ⅰ基于自噬升高白细胞作用研究[J].中草药，2018，49(14):3350-3356.
27.邹娅，徐应淑，熊永爱*，等.地榆皂苷自乳化药物传递系统的制备及质量评价[J].中草药，2018，49(06):1317-1323.
28.熊永爱，杨明.地榆鞣质与皂苷组分配伍对儿茶素、表儿茶素和地榆皂苷Ⅰ在大鼠体内药动学参数的影响[J].中国中药杂志，2016，41(19):3661-3667.
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